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Novel Antibody Therapies Market for advanced stage drugs is anticipated to grow at a CAGR of 36% by 2035

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Novel Antibody Therapies
Novel Antibody Therapies

Owing to the recent approval of therapies, such as Elzonris®, and Pluvicto®, there has been a substantial increase in the R&D activity to evaluate the use of novel antibody therapy candidates for the treatment of a variety of disease indications

Roots Analysis has announced the addition of “Novel Antibody Therapies Market, 2022-2035” report to its list of offerings.

Antibodies are the key components of immune system that bind to specific markers on cells or tissues, thereby offering first line of defense against multiple disorders. This has opened a new target space for the development of antibody therapeutics and techniques, facilitating tools to uniquely distinct malignantly transformed cells from regular cells.

Key Market Insights

Till date, five novel antibody therapies have been marketed and close to 80% of the pipeline candidates are under clinical evaluation. It is worth mentioning that most of the drug candidates are immunotoxins (34%), followed by immunocytokines (32.5%). Majority of these therapies are under clinical trials for the treatment of lymphoma (22) followed by solid tumors (19) and leukemia (18).

Around 60 industry and non-industry players are engaged in the development of novel antibody therapies, globally

North America has emerged as the hub, featuring the presence of approximately 60% developers. The market is currently dominated by the presence of small players (27%). Interestingly, 16% of the players are big pharma companies engaged in the development of such therapeutics for multiple target indications.

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Popular journals that have published multiple articles include Cancer, Frontiers in Immunology, International Journal of Molecular Sciences and Scientific Reports.

Partnership activity in this field has increased at a CAGR of over 55%, since 2018

Around 50% of the reported deals were established post-2021, indicating a recent rise in the interest of players engaged in this domain. It is worth highlighting that majority of the agreements were supply agreements (19%), followed by product development and commercialization agreements (15%).

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Key Questions Answered

  • Who are the leading industry and non-industry players engaged in the development of novel antibody therapies
  • Which geographies are the most active in conducting clinical trials related to novel antibody therapies?
  • What is the focus area of various publications related to novel antibody therapies?
  • Which are the leading funding institutes/centers supporting research related to novel antibody therapies?

A detailed market forecast, featuring analysis of the current and projected future opportunity across key market segments (listed below)

Target disease Indication(s)

  • Acute Myeloid Leukemia
  • Advanced / Metastatic soft-tissue sarcoma
  • Melanoma
  • Diffuse Large B-cell Lymphoma
  • Bladder Cancer
  • Prostate Cancer
  • Graft-versus-host disease

Type of Novel Antibody

  • Immunocytokines
  • Immunotoxins
  • Radioisotope immunoconjugates

Type of Therapy

  • Combination Therapy
  • Monotherapy
  • Route of Administration
  • Intravenous
  • Intravesical
  • Intratumoral

Geographical Region

  • North America
  • Europe
  • Asia-Pacific

Key companies covered in the report

  • Actinium Pharmaceuticals
  • Molecular Templates
  • Philogen
  • Roche
  • Seagen
  • Sesen bio
  • Telix Pharmaceuticals
  • Y-mAbs Therapeutics

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